Temporin-SHa peptide
For research use only. NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE.
Catalog Number: MPE0008194
Product Quantity: 5mg/20mg
Price: Varies
Availability: In Stock
Product Information
C-terminal NH2. Active against S. aureus ATCC 25923 (MIC 3 uM), E. faecalis ATCC 29212 (MIC 10 uM), B. megaterium (2 uM), Gram-negative E. coli ATCC 25922 (MIC 10 uM), E. coli ATCC 35218 (MIC 10 uM), P. aeruginosa ATCC 27853 (MIC 20 uM), fungi C. albicans ATCC 90028 (MIC 16 uM), C. parapsilosis ATCC 22019 (MIC 31 uM), and S. cerevisiae (MIC 8 uM). 50% hemolysis at 25 uM. The peptide is helical in 40% TFE based on CD. 3D structure bound to SDS micelles is known with the three glycines on the polar surface (Biochemistry 2008; 47: 10513-25). Updated 3/2014. Temporin-SHa has Antibacterial, Antifungal activity. The source of Temporin-SHa is Pelophylax saharica , North Africa.
| Product Name: | Temporin-SHa peptide |
| Sequence: | FLSGIVGMLGKLF |
| Three letter code: | Phe-Leu-Ser-Gly-Ile-Val-Gly-Met-Leu-Gly-Lys-Leu-Phe |
| Length (aa): | 13 |
| Peptide Purity (HPLC): | >95%; 98% and 99% purity available upon request |
| Quantity/Unit: | 1 Vial |
| * Optional Service: | TFA Removal Service is available upon request. |
Technical Information
| Source: | Synthetic |
| Storage Guidelines: | Store at -20°C for up to 1 year. should be refrigerated after reconstitution. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides |
| Solubility: | Soluble in water |
| Appearance: | White to off-white powder |
| Shipping: | Peptides are shipped at ambient temperature by standard shipment process. |
| About TFA salt: | Trifluoroacetic acid (TFA) is a strong acid, which is commonly used to cleave synthesized peptides from solid-phase resins and is also used to improve HPLC performance in the peptide purification step. By default, custom peptides are delivered as lyophilized TFA salts, and can contain as much as 10-45% TFA. TFA in custom peptides can cause inexplicable discrepancies in subsequent assay data. For instance, TFA in nM concentrations has been shown to interfere with cellular assays, inhibiting cellular proliferation in some instances, and increasing cell viability in others. It has also been found to be an unintended allosteric modulator of the glycine receptor, GlyR. TFA Removal Service is recommended for: > Peptides that will be used in cellular assays > Peptides that will be used as APIs or in manufactured products > For hydrophilic peptides containing numerous basic residues |
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Custom Peptide Synthesis: Temporin-SHa peptide peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression. Read more...
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