Sarconesin II peptide
For research use only. NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE.
Catalog Number: MPE0004925
Product Quantity: 5mg/20mg
Price: Varies
Availability: In Stock
Product Information
Sarconesin II is a new antimicrobial peptides isolated from Sarconesiopsis magellanica excretions and secretions. Sarconesin II was documented as a conserved domain of the ATP synthase protein belonging to the Fli-1 superfamily. A BLAST search for Calliphoridae multiple sequence alignment revealed sarconesin II’s 100% matching identity with the mitochondrial ATP synthase subunit beta, appearing as a putative conserved domain of the Fli-1 superfamily: flagellar biosynthesis/type III secretory pathway ATPase (Accession: cl25576). Sarconesin II and the conserved domain also appeared in other organisms, such as Homo sapiens (Sequence ID: gi|179279|AAA51808.1), Drosophila melanogaster (gi|442614522|NP_001259081.1) and Mus musculus (gi|31980648|NP_058054.2). Sarconesin II is predicted to have a typical alpha-helix structure. Sarconesin II induced alterations in E. coli cell morphology. Sarconesin II had good activity against Gram-negative and Gram-positive bacteria, including E. coli K12 MG1655.
| Product Name: | Sarconesin II peptide |
| Molecular Formula: | C67H106N16O19 |
| Molecular Weight: | 1439.65 |
| Sequence: | H-VALTGLTVAEYFR-OH |
| Three letter code: | H-Val-Ala-Leu-Thr-Gly-Leu-Thr-Val-Ala-Glu-Tyr-Phe-Arg-OH |
| Length (aa): | 18 |
| Peptide Purity (HPLC): | >95%; 98% and 99% purity available upon request |
| Quantity/Unit: | 1 Vial |
| * Optional Service: | TFA Removal Service is available upon request. |
Technical Information
| Source: | Synthetic |
| Storage Guidelines: | Store at -20°C for up to 1 year. should be refrigerated after reconstitution. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides |
| Solubility: | Soluble in water |
| Appearance: | White to off-white powder |
| Shipping: | Peptides are shipped at ambient temperature by standard shipment process. |
| About TFA salt: | Trifluoroacetic acid (TFA) is a strong acid, which is commonly used to cleave synthesized peptides from solid-phase resins and is also used to improve HPLC performance in the peptide purification step. By default, custom peptides are delivered as lyophilized TFA salts, and can contain as much as 10-45% TFA. TFA in custom peptides can cause inexplicable discrepancies in subsequent assay data. For instance, TFA in nM concentrations has been shown to interfere with cellular assays, inhibiting cellular proliferation in some instances, and increasing cell viability in others. It has also been found to be an unintended allosteric modulator of the glycine receptor, GlyR. TFA Removal Service is recommended for: > Peptides that will be used in cellular assays > Peptides that will be used as APIs or in manufactured products > For hydrophilic peptides containing numerous basic residues |
Related Products / Services
Custom Peptide Synthesis: Sarconesin II peptide peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression. Read more...
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