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    S6 Phosphate Acceptor Peptide, S6-1

    For research use only. NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE.

    Catalog Number: MPE0007443

    Product Quantity: 5mg/20mg

    Price: Varies

    Availability: In Stock

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    Product Information

    This peptide is based on the sequence of a region of rat hepatic ribosomal protein S6 which contains the major phosphorylation site for cAMP-dependent protein kinase and one of the insulin-stimulated phosphorylation sites. It has been shown to be a substrate for cAMP-dependent protein kinase, for protein kinase C, and for the ribosomal protein S6 kinases (p70S6K and p85S6K isoforms, as well as insulin-stimulated p90rsk).

    Product Name: S6 Phosphate Acceptor Peptide, S6-1
    Molecular Formula: C39H75N17O11
    Molecular Weight: 958.13
    Sequence: RRLSSLRA
    Three letter code: H-Arg-Arg-Leu-Ser-Ser-Leu-Arg-Ala-OH
    Length (aa): 8
    Peptide Purity (HPLC): >95%; 98% and 99% purity available upon request
    Quantity/Unit: 1 Vial
    * Optional Service: TFA Removal Service is available upon request.

    Technical Information

    Source: Synthetic
    Storage Guidelines: Store at -20°C for up to 1 year. should be refrigerated after reconstitution. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
    Solubility: Soluble in water
    Appearance: White to off-white powder
    Shipping: Peptides are shipped at ambient temperature by standard shipment process.
    About TFA salt: Trifluoroacetic acid (TFA) is a strong acid, which is commonly used to cleave synthesized peptides from solid-phase resins and is also used to improve HPLC performance in the peptide purification step. By default, custom peptides are delivered as lyophilized TFA salts, and can contain as much as 10-45% TFA.
    TFA in custom peptides can cause inexplicable discrepancies in subsequent assay data. For instance, TFA in nM concentrations has been shown to interfere with cellular assays, inhibiting cellular proliferation in some instances, and increasing cell viability in others. It has also been found to be an unintended allosteric modulator of the glycine receptor, GlyR.
    TFA Removal Service is recommended for: > Peptides that will be used in cellular assays > Peptides that will be used as APIs or in manufactured products > For hydrophilic peptides containing numerous basic residues

    Related Products / Services

    Custom Peptide Synthesis:   S6 Phosphate Acceptor Peptide, S6-1 peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression. Read more...

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