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    Pre-S2 (1-26) peptide

    For research use only. NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE.

    Catalog Number: MPE0001405

    Product Quantity: 5mg/20mg

    Price: Varies

    Availability: In Stock

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    Product Information

    This synthetic peptide comprises the N-terminal portion of a 55-residue sequence encoded by the pre-S2 region of hepatitis B virus (HBV) DNA. It represents an immunodominant epitope, and the immunogenicity can be enhanced by covalently linking the peptide to liposomes. Antibodies elicited against this determinant recognize envelope epitopes common to several subtypes of HBV and HBsAg particles. Because these antibodies show virusneutralizing activity in vivo, pre-S (120-145) has the potential as

    Product Name: Pre-S2 (1-26) peptide
    Molecular Formula: C131H199N39O37S
    Molecular Weight: 2944.33
    Sequence: MQWNSTAFHQTLQDPRVRGLYLPAGG
    Three letter code: H-Met-Gln-Trp-Asn-Ser-Thr-Ala-Phe-His-Gln-Thr-Leu-Gln-Asp-Pro-Arg-Val-Arg-Gly-Leu-Tyr-Leu-Pro-Ala-Gly-Gly-OH
    Length (aa): 26
    Peptide Purity (HPLC): >95%; 98% and 99% purity available upon request
    Quantity/Unit: 1 Vial
    * Optional Service: TFA Removal Service is available upon request.

    Technical Information

    Source: Synthetic
    Storage Guidelines: Store at -20°C for up to 1 year. should be refrigerated after reconstitution. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
    Solubility: Soluble in water
    Appearance: White to off-white powder
    Shipping: Peptides are shipped at ambient temperature by standard shipment process.
    About TFA salt: Trifluoroacetic acid (TFA) is a strong acid, which is commonly used to cleave synthesized peptides from solid-phase resins and is also used to improve HPLC performance in the peptide purification step. By default, custom peptides are delivered as lyophilized TFA salts, and can contain as much as 10-45% TFA.
    TFA in custom peptides can cause inexplicable discrepancies in subsequent assay data. For instance, TFA in nM concentrations has been shown to interfere with cellular assays, inhibiting cellular proliferation in some instances, and increasing cell viability in others. It has also been found to be an unintended allosteric modulator of the glycine receptor, GlyR.
    TFA Removal Service is recommended for: > Peptides that will be used in cellular assays > Peptides that will be used as APIs or in manufactured products > For hydrophilic peptides containing numerous basic residues

    Related Products / Services

    Custom Peptide Synthesis:   Pre-S2 (1-26) peptide peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression. Read more...

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