Odorranain-B1 peptide
For research use only. NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE.
Catalog Number: MPE0005143
Product Quantity: 5mg/20mg
Price: Varies
Availability: In Stock
Product Information
The peptide has been reported in different articles in different names. In addition to antimicrobial activity, the peptide also inhibits trypsin due to the disulfide-bonded trypsin inhibitory loop in the sequence (enzyme inhibitor) (Li J et al 2007 FASEB J 21: 2466-73). In this proteomic paper, 372 cDNA sequences of antimicrobial peptides were found in a single frog. Among them, 107 are new peptides. Approximately 40 peptides were synthesized and tested. Only 24 peptides with antimicrobial acitivities (APD entries 1291-1314) were registered into this database. OBR1 is active against E. coli ATCC25922 (MIC 5.83 ug/ml), S. aureus ATCC2592 (MIC 5.83 ug/ml), B. dysenteria (1.84 ug/ml), and C. albicans ATCC2002 (2.4 ug/ml). Derivatives: ORB-C (sequence CWTKSIPPKPC, disulfide bridged) has improved trypsin inhibition ability but lost its antimicrobial activity. ORB1 is N-terminal AA truncated form. Odorranain-B1 has Antibacterial, Antifungal activity. The source of Odorranain-B1 is Odorrana grahami, Asia.
| Product Name: | Odorranain-B1 peptide |
| Sequence: | AALKGCWTKSIPPKPCFGKR |
| Three letter code: | Ala-Ala-Leu-Lys-Gly-Cys-Trp-Thr-Lys-Ser-Ile-Pro-Pro-Lys-Pro-Cys-Phe-Gly-Lys-Arg |
| Length (aa): | 20 |
| Peptide Purity (HPLC): | >95%; 98% and 99% purity available upon request |
| Quantity/Unit: | 1 Vial |
| * Optional Service: | TFA Removal Service is available upon request. |
Technical Information
| Source: | Synthetic |
| Storage Guidelines: | Store at -20°C for up to 1 year. should be refrigerated after reconstitution. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides |
| Solubility: | Soluble in water |
| Appearance: | White to off-white powder |
| Shipping: | Peptides are shipped at ambient temperature by standard shipment process. |
| About TFA salt: | Trifluoroacetic acid (TFA) is a strong acid, which is commonly used to cleave synthesized peptides from solid-phase resins and is also used to improve HPLC performance in the peptide purification step. By default, custom peptides are delivered as lyophilized TFA salts, and can contain as much as 10-45% TFA. TFA in custom peptides can cause inexplicable discrepancies in subsequent assay data. For instance, TFA in nM concentrations has been shown to interfere with cellular assays, inhibiting cellular proliferation in some instances, and increasing cell viability in others. It has also been found to be an unintended allosteric modulator of the glycine receptor, GlyR. TFA Removal Service is recommended for: > Peptides that will be used in cellular assays > Peptides that will be used as APIs or in manufactured products > For hydrophilic peptides containing numerous basic residues |
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Custom Peptide Synthesis: Odorranain-B1 peptide peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression. Read more...
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