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    Mastoparan M peptide

    For research use only. NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE.

    Catalog Number: MPE0008826

    Product Quantity: 5mg/20mg

    Price: Varies

    Availability: In Stock

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    Product Information

    Active against Gram-positive S. aureus ATCC25923, E. faecalis ATCC29212, S. aureus IS 10# (MIC 2.5-5 uM), S. aureus IS 37#, Gram-negative E. coli ATCC25922, E. cloacae ATCC13047, K. pneumonia ATCC700603 (MIC 10-20 uM), B. pyocyaneus CMCCB1010 (MIC 40 uM), P. aeruginosa ATCC27853, B. dysenteriae (MIC 5 uM), E. coli IS 37# (MIC 10 uM), E. coli IS 117# (MIC 40 uM), E. coli IS 218#, P. aeruginosa IS 350# (MIC 20 uM), K. pneumonia IS 59# (MIC 10 uM), fungi C. albicans ATCC2002, C. albicans ATCC90028 (MIC 10 uM), and C. parapsilosis ATCC22019 (MIC 40 uM) (Yang et al., 2013). Mastoparan M made in all D-amino acids showed 2-fold higher antibacterial activity than L-mastoparan M (Li ML et al 2000 Int J Antimicrob Agents. 13(3):203-8). The same peptide is also expressed in Vespa magnifica (Xu X et al, 2006) and Vespa tropica (Yang et al., 2013). Found in multiple species. Updated 3/2014; 4/2014 Mastoparan M has Antimicrobial activity. The source of Mastoparan M is Hornet Vespa mandarinia ; venom gland, the social wasp Vespa tropica; wasp venom, Vespa magnifica.

    Product Name: Mastoparan M peptide
    Molecular Formula: C70H130N18O16
    Molecular Weight: 1478.9
    Sequence: INLKAIAALAKKLL
    Three letter code: H-Ile-Asn-Leu-Lys-Ala-Ile-Ala-Ala-Leu-Ala-Lys-Lys-Leu-Leu-OH
    Length (aa): 14
    Peptide Purity (HPLC): >95%; 98% and 99% purity available upon request
    Quantity/Unit: 1 Vial
    * Optional Service: TFA Removal Service is available upon request.

    Technical Information

    Source: Synthetic
    Storage Guidelines: Store at -20°C for up to 1 year. should be refrigerated after reconstitution. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
    Solubility: Soluble in water
    Appearance: White to off-white powder
    Shipping: Peptides are shipped at ambient temperature by standard shipment process.
    About TFA salt: Trifluoroacetic acid (TFA) is a strong acid, which is commonly used to cleave synthesized peptides from solid-phase resins and is also used to improve HPLC performance in the peptide purification step. By default, custom peptides are delivered as lyophilized TFA salts, and can contain as much as 10-45% TFA.
    TFA in custom peptides can cause inexplicable discrepancies in subsequent assay data. For instance, TFA in nM concentrations has been shown to interfere with cellular assays, inhibiting cellular proliferation in some instances, and increasing cell viability in others. It has also been found to be an unintended allosteric modulator of the glycine receptor, GlyR.
    TFA Removal Service is recommended for: > Peptides that will be used in cellular assays > Peptides that will be used as APIs or in manufactured products > For hydrophilic peptides containing numerous basic residues

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    Custom Peptide Synthesis:   Mastoparan M peptide peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression. Read more...

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