Hymenochirin-1Pa peptide
For research use only. NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE.
Catalog Number: MPE0010129
Product Quantity: 5mg/20mg
Price: Varies
Availability: In Stock
Product Information
Active against a broad spectrum of pathogens, including multiple S. aureus, S. epidermidis, A. baumannii strains, E. coli ATCC 25726, S. maltophilia (MIC 0.6-5 uM), K. pneumoniae ATCC 700603 (MIC 10 uM), E. faecalis ATCC 29212, P. aeruginosa ATCC 27853 (MIC 20 uM), and weakly against C. albicans (MIC 80 uM). Also active against human non-small lung adenocarcinoma A549 cells, breast adenocarcinoma MDA-MB-231 cells, and colorectal adenocarcinoma HT-29 cells. Its applications as antibacterial and anticancer agents may be limited due to hemolytic ability. However, the D9K mutant is not hemolytic. In TFE, residues 6-17 and 21-28 are helical (Serra et al. 2014). Reg. 09/23/2014. The source of Hymenochirin-1Pa is skin secretions, Merlin's clawed frog, Pseudhymenochirus merlini, Africa.
| Product Name: | Hymenochirin-1Pa peptide |
| Sequence: | LKLSPKTKDTLKKVLKGAIKGAIAIASMA |
| Three letter code: | Leu-Lys-Leu-Ser-Pro-Lys-Thr-Lys-Asp-Thr-Leu-Lys-Lys-Val-Leu-Lys-Gly-Ala-Ile-Lys-Gly-Ala-Ile-Ala-Ile-Ala-Ser-Met-Ala |
| Length (aa): | 29 |
| Peptide Purity (HPLC): | >95%; 98% and 99% purity available upon request |
| Quantity/Unit: | 1 Vial |
| * Optional Service: | TFA Removal Service is available upon request. |
Technical Information
| Source: | Synthetic |
| Storage Guidelines: | Store at -20°C for up to 1 year. should be refrigerated after reconstitution. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides |
| Solubility: | Soluble in water |
| Appearance: | White to off-white powder |
| Shipping: | Peptides are shipped at ambient temperature by standard shipment process. |
| About TFA salt: | Trifluoroacetic acid (TFA) is a strong acid, which is commonly used to cleave synthesized peptides from solid-phase resins and is also used to improve HPLC performance in the peptide purification step. By default, custom peptides are delivered as lyophilized TFA salts, and can contain as much as 10-45% TFA. TFA in custom peptides can cause inexplicable discrepancies in subsequent assay data. For instance, TFA in nM concentrations has been shown to interfere with cellular assays, inhibiting cellular proliferation in some instances, and increasing cell viability in others. It has also been found to be an unintended allosteric modulator of the glycine receptor, GlyR. TFA Removal Service is recommended for: > Peptides that will be used in cellular assays > Peptides that will be used as APIs or in manufactured products > For hydrophilic peptides containing numerous basic residues |
Related Products / Services
Custom Peptide Synthesis: Hymenochirin-1Pa peptide peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression. Read more...
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