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    Dermaseptin-SP2 peptide

    For research use only. NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE.

    Catalog Number: MPE0000515

    Product Quantity: 5mg/20mg

    Price: Varies

    Availability: In Stock

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    Product Information

    Among the antimicrobial peptides, dermaseptin-SP2 was the most potent, inhibiting Escherichia coli, Staphylococcus aureus, and ORSA with a minimum inhibitory concentration (MIC) of 2.68 M, and Candida albicans with an MIC of10.71 uM, without haemolytic eects. The peptides described in this study represent but a superficial glance at the considerable structural diversity of bioactive peptides produced in the skin secretion of A. spurrelli.

    Product Name: Dermaseptin-SP2 peptide
    Molecular Formula: C134H222N38O37S
    Molecular Weight: 2989.48
    Sequence: H-ASWKVFLKNIGKAAGKAVLNSVTDMVNQ-Amidation
    Three letter code: H-Ala-Ser-Trp-Lys-Val-Phe-Leu-Lys-Asn-Ile-Gly-Lys-Ala-Ala-Gly-Lys-Ala-Val-Leu-Asn-Ser-Val-Thr-Asp-Met-Val-Asn-Gln-Amidation
    Length (aa): 40
    Peptide Purity (HPLC): >95%; 98% and 99% purity available upon request
    Quantity/Unit: 1 Vial
    * Optional Service: TFA Removal Service is available upon request.

    Technical Information

    Source: Synthetic
    Storage Guidelines: Store at -20°C for up to 1 year. should be refrigerated after reconstitution. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
    Solubility: Soluble in water
    Appearance: White to off-white powder
    Shipping: Peptides are shipped at ambient temperature by standard shipment process.
    About TFA salt: Trifluoroacetic acid (TFA) is a strong acid, which is commonly used to cleave synthesized peptides from solid-phase resins and is also used to improve HPLC performance in the peptide purification step. By default, custom peptides are delivered as lyophilized TFA salts, and can contain as much as 10-45% TFA.
    TFA in custom peptides can cause inexplicable discrepancies in subsequent assay data. For instance, TFA in nM concentrations has been shown to interfere with cellular assays, inhibiting cellular proliferation in some instances, and increasing cell viability in others. It has also been found to be an unintended allosteric modulator of the glycine receptor, GlyR.
    TFA Removal Service is recommended for: > Peptides that will be used in cellular assays > Peptides that will be used as APIs or in manufactured products > For hydrophilic peptides containing numerous basic residues

    Related Products / Services

    Custom Peptide Synthesis:   Dermaseptin-SP2 peptide peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression. Read more...

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