AS10 peptide
For research use only. NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE.
Catalog Number: MPE0011188
Product Quantity: 5mg/20mg
Price: Varies
Availability: In Stock
Product Information
Shorter peptides based on CRAMP, such as AS10 (KLKKIAQKIKNFFQKLVP), were also able to inhibit Candida albicans biofilm growth on Ti disks as well as formation of biofilms from other bacteria. The study also tested the effect of AS10 on human osteoblasts, mesenchymal stromal cells, and endothelial cells in vitro and demonstrated no negative effects on cell viability. Further, AS10 did not interfere with calcium deposition by the osteoblasts or mesenchymal stromal cells or with tube formation by the endothelial cells, which suggests that AS10 could be used as an anti-biofilm coating on implants without affecting cells in the surrounding tissues.
| Product Name: | AS10 peptide |
| Molecular Formula: | C105H179N27O22 |
| Molecular Weight: | 2171.7 |
| Sequence: | H-KLKKIAQKIKNFFQKLVP-OH |
| Three letter code: | H-Lys-Leu-Lys-Lys-Ile-Ala-Gln-Lys-Ile-Lys-Asn-Phe-Phe-Gln-Lys-Leu-Val-Pro-OH |
| Length (aa): | 23 |
| Peptide Purity (HPLC): | >95%; 98% and 99% purity available upon request |
| Quantity/Unit: | 1 Vial |
| * Optional Service: | TFA Removal Service is available upon request. |
Technical Information
| Source: | Synthetic |
| Storage Guidelines: | Store at -20°C for up to 1 year. should be refrigerated after reconstitution. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides |
| Solubility: | Soluble in water |
| Appearance: | White to off-white powder |
| Shipping: | Peptides are shipped at ambient temperature by standard shipment process. |
| About TFA salt: | Trifluoroacetic acid (TFA) is a strong acid, which is commonly used to cleave synthesized peptides from solid-phase resins and is also used to improve HPLC performance in the peptide purification step. By default, custom peptides are delivered as lyophilized TFA salts, and can contain as much as 10-45% TFA. TFA in custom peptides can cause inexplicable discrepancies in subsequent assay data. For instance, TFA in nM concentrations has been shown to interfere with cellular assays, inhibiting cellular proliferation in some instances, and increasing cell viability in others. It has also been found to be an unintended allosteric modulator of the glycine receptor, GlyR. TFA Removal Service is recommended for: > Peptides that will be used in cellular assays > Peptides that will be used as APIs or in manufactured products > For hydrophilic peptides containing numerous basic residues |
Related Products / Services
Custom Peptide Synthesis: AS10 peptide peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression. Read more...
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